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Company ReportsPuma Biotechnology
Puma Biotechnology(PBYI)
Puma Biotechnology is a publicly traded biopharmaceutical company (NASDAQ: PBYI) headquartered in Los Angeles, CA.
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Trade Name
Drug Name
Approved
Patent Expires
Indication
NerlynxNeratinib2017-07-172025-2031
Breast neoplasms
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Neratinib
breast neoplasms
,
biliary tract neoplasms
,
neoadjuvant therapy
Benzimidazole
healthy volunteers/patients
,
inflammatory bowel diseases
,
intestinal diseases
,
rheumatoid arthritis
,
arthritis
,
osteoarthritis
Aglatimagene besadenovec
prostatic neoplasms
Alisertib
lung neoplasms
,
small cell lung carcinoma
,
breast neoplasms
Edrecolomab
myelodysplastic syndromes
,
preleukemia
,
syndrome
,
large b-cell lymphoma diffuse
,
multiple myeloma
,
non-hodgkin lymphoma
,
lymphoma
,
b-cell lymphoma
,
b-cell chronic lymphocytic leukemia
,
residual neoplasm
,
lung neoplasms
,
small cell lung carcinoma
,
neuroendocrine carcinoma
,
breast neoplasms
Lornoxicam
sarcoma
,
hiv
,
acquired immunodeficiency syndrome
,
kaposi sarcoma
,
human herpesvirus 8
Aspartame
neutropenia
Bevifimod
healthy volunteers/patients
Nepidermin
atrial fibrillation
,
atrial flutter
Polyglycolic acid
renal cell carcinoma
,
digestive system neoplasms
,
gastrointestinal stromal tumors
,
neoplasm metastasis
,
colonic neoplasms
,
rectal neoplasms
,
ovarian neoplasms
,
lung neoplasms
,
colorectal neoplasms
,
neoplasms
,
pancreatic neoplasms
,
stomach neoplasms
,
adenocarcinoma
,
fever
,
hereditary autoinflammatory diseases
,
amyloidosis
,
familial mediterranean fever
Globulin, immune
healthy volunteers/patients
,
myeloid leukemia
,
head and neck neoplasms
,
myelodysplastic syndromes
,
preleukemia
,
uveal neoplasms
,
cutaneous malignant melanoma
,
uveal melanoma
,
endometrial neoplasms
,
uveitis
,
melanoma
,
multiple myeloma
,
mantle-cell lymphoma
,
glioma
,
esophageal neoplasms
,
syndrome
,
hiv infections
,
biliary tract neoplasms
,
plasma cell neoplasms
,
choroidal neovascularization
,
sarcoma
,
waldenstrom macroglobulinemia
,
b-cell lymphoma marginal zone
,
aids-related lymphoma
,
bronchiolitis obliterans syndrome
,
unknown primary neoplasms
,
genomic instability
,
type 1 diabetes mellitus
,
cholangiocarcinoma
,
meningeal carcinomatosis
,
coronary disease
,
coronary artery disease
,
myocardial ischemia
,
heart diseases
,
vascular graft occlusion
,
margins of excision
,
neuroblastoma
,
hemolytic-uremic syndrome
,
thrombotic thrombocytopenic purpura
,
thrombocytopenic purpura
,
purpura
,
azotemia
,
behcet syndrome
,
extranodal nk-t-cell lymphoma
,
hereditary sensory and autonomic neuropathies
,
graft vs host disease
,
castleman disease
,
kaposi sarcoma
,
systemic lupus erythematosus
,
sjogren's syndrome
,
diabetic nephropathies
,
hypertension
,
renal hypertension
,
diabetes mellitus
,
nasopharyngeal carcinoma
,
nasopharyngeal neoplasms
,
central nervous system neoplasms
,
nervous system neoplasms
,
pathologic neovascularization
,
burkitt lymphoma
,
precursor b-cell lymphoblastic leukemia-lymphoma
,
sex cord-gonadal stromal tumors
,
interstitial lung diseases
,
erythema multiforme
,
reactive arthritis
,
immunoblastic lymphadenopathy
,
myositis
,
myasthenia gravis
,
neuroendocrine carcinoma
,
lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
liver neoplasms
,
follicular lymphoma
,
hepatocellular carcinoma
,
rectal neoplasms
,
triple negative breast neoplasms
,
glioblastoma
,
renal cell carcinoma
,
neoplasm metastasis
,
macular degeneration
,
adenocarcinoma
,
carcinoma
,
pancreatic neoplasms
,
macular edema
,
colonic neoplasms
,
recurrence
,
small cell lung carcinoma
,
ovarian epithelial carcinoma
,
urinary bladder neoplasms
,
lung neoplasms
,
esophageal squamous cell carcinoma
,
uterine cervical neoplasms
,
urologic neoplasms
,
transitional cell carcinoma
,
inflammatory breast neoplasms
,
ulcerative colitis
,
anti-neutrophil cytoplasmic antibody-associated vasculitis
,
brain neoplasms
,
myeloid leukemia acute
,
prostatic neoplasms
,
thrombocytopenic purpura idiopathic
,
nasal polyps
,
circulating neoplastic cells
,
malignant mesothelioma
,
diabetic retinopathy
,
multiple sclerosis
,
mucinous adenocarcinoma
,
ductal carcinoma breast
,
hematologic neoplasms
,
hemolysis
,
vasculitis
,
iga glomerulonephritis
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
castration-resistant prostatic neoplasms
,
retinal diseases
,
vision disorders
,
eye diseases
,
pemphigus
,
chronic progressive multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
neuromyelitis optica
,
myelin oligodendrocyte glycoprotein antibody-associated disease
,
guillain-barre syndrome
,
patient preference
,
lymphoproliferative disorders
,
neoplasms by histologic type
,
neoplasms by site
,
salivary gland neoplasms
,
skin neoplasms
,
gallbladder neoplasms
,
colitis
,
systemic vasculitis
,
disability evaluation
,
cognition disorders
,
anemia
,
hemolytic anemia autoimmune
,
malignant pleural effusion
,
nephrotic syndrome
,
focal segmental glomerulosclerosis
,
lipoid nephrosis
,
ankylosing spondylitis
,
retinal neovascularization
,
membranous glomerulonephritis
,
breast neoplasms
,
colorectal neoplasms
,
non-small-cell lung carcinoma
,
rheumatoid arthritis
,
neoplasms
,
non-hodgkin lymphoma
,
b-cell chronic lymphocytic leukemia
,
leukemia
,
lymphoid leukemia
,
ovarian neoplasms
,
stomach neoplasms
,
kidney transplantation
,
chronic kidney failure
,
granulomatosis with polyangiitis
,
arthritis
,
microscopic polyangiitis
,
fallopian tube neoplasms
,
heart transplantation
,
kidney diseases
,
peritoneal neoplasms
,
pulmonary fibrosis
,
immunosuppression therapy
,
graft rejection
,
asthma
,
transplantation
,
renal insufficiency
,
food hypersensitivity
,
covid-19
,
hepatitis b
,
hepatitis
,
hepatitis a
,
adenocarcinoma of lung
,
off-label use
,
retinal vein occlusion
,
hemophilia a
,
antiphospholipid syndrome
,
sars-cov-2
,
infections
,
severe acute respiratory syndrome
,
communicable diseases
,
hiv
,
hepatitis c
,
acquired immunodeficiency syndrome
,
neoadjuvant therapy
,
molecular targeted therapy
,
liver cirrhosis
,
atopic dermatitis
Digitalis
breast neoplasms
,
bacterial infections
,
epilepsy
,
type 2 diabetes mellitus
,
hypertension
,
pre-eclampsia
Hyoscyamine
insulin resistance
,
healthy volunteers/patients
,
prediabetic state
,
hypoglycemia
,
autonomic nervous system diseases
,
orthostatic intolerance
,
depression
,
death
,
status asthmaticus
,
glucose intolerance
,
digestive system physiological phenomena
,
gastrointestinal motility
,
leukemia
,
acute disease
,
near-infrared spectroscopy
,
gastric bypass
,
gastrectomy
,
vasodilation
,
vasoconstriction
,
allergic rhinitis
,
orthostatic hypotension
,
nervous system diseases
,
primary dysautonomias
,
cerebral palsy
,
spinal fractures
,
pharmacokinetics
,
sialorrhea
,
breast neoplasms
,
lung neoplasms
,
neoplasms
,
hemorrhage
,
non-small-cell lung carcinoma
,
brain neoplasms
,
colonic neoplasms
,
rhinitis
,
allergic rhinitis seasonal
,
heart arrest
,
alveolar soft part sarcoma
,
hemostatic disorders
,
adenocarcinoma
,
granulosa cell tumor
,
amyotrophic lateral sclerosis
,
respiration
,
regional blood flow
,
ocular physiological phenomena
,
parkinson disease
,
photophobia
,
ventilator-associated pneumonia
,
pneumonia
,
neutropenia
,
pancreatic neoplasms
,
ductal carcinoma
,
eye axial length
,
degenerative myopia
,
obstructive lung diseases
,
general anesthesia
,
emergence delirium
,
lymphoma
,
uveitis
,
premedication
,
replacement arthroplasty hip
,
chest pain
,
anisometropia
,
carcinoma
,
eye diseases
,
hypospadias
,
anterior uveitis
,
iridocyclitis
,
blood pressure
,
anesthesia and analgesia
,
heart rate
,
stomach neoplasms
,
neoplasm metastasis
,
retinal diseases
,
retinopathy of prematurity
,
cerebral infarction
,
replacement arthroplasty knee
,
hip fractures
,
blood coagulation
,
familial dysautonomia
,
vision disorders
,
strabismus
,
colorectal neoplasms
,
recurrence
,
squamous cell carcinoma
,
esophageal squamous cell carcinoma
,
myopia
,
chronic obstructive pulmonary disease
,
neuromuscular blockade
,
asthma
,
anesthesia
,
postoperative pain
,
hypotension
,
bradycardia
,
delayed emergence from anesthesia
,
lung diseases
,
amblyopia
,
vomiting
,
postoperative nausea and vomiting
,
drug-related side effects and adverse reactions
,
nausea
,
cesarean section
,
organophosphate poisoning
,
poisoning
,
spinal anesthesia
,
respiratory distress syndrome
,
motor activity
,
disease progression
,
intratracheal intubation
,
newborn respiratory distress syndrome
,
dyspnea
,
cognitive dysfunction
,
muscle hypotonia
,
post-dural puncture headache
,
cardiac arrhythmias
,
syndrome
,
pregnancy
,
premature birth
,
disease
,
apnea
,
respiratory aspiration
,
acute pain
,
respiratory insufficiency
,
pulmonary atelectasis
,
cataract
,
tachycardia
,
retinal detachment
,
emergencies
,
alzheimer disease
,
laparoscopy
,
fibrosis
,
muscle relaxation
,
obstructive sleep apnea
,
sleep apnea syndromes
,
pain
,
hypoxia
,
intubation
,
wounds and injuries
,
shock
,
hip osteoarthritis
,
refractive errors
,
osteoarthritis
,
conscious sedation
,
myocardial infarction
,
cholelithiasis
,
signs and symptoms
,
cognition disorders
,
neurocognitive disorders
,
postoperative period
,
anesthesia recovery period
,
liver diseases
,
liver cirrhosis
,
shoulder pain
,
newborn infant diseases
,
dental care for persons with disabilities
,
mydriasis
,
headache
,
nephrolithiasis
,
kidney calculi
,
lower urinary tract symptoms
,
esophageal achalasia
,
respiratory tract infections
,
cold temperature
,
exercise-induced asthma
,
sepsis
,
bronchiolitis obliterans syndrome
,
anosmia
,
hepatocellular carcinoma
,
muscle weakness
,
infarction
,
heart block
,
inferior wall myocardial infarction
,
pleural effusion
,
mesothelioma
,
malignant pleural effusion
,
lymphadenopathy
,
pleural empyema
,
empyema
,
pneumothorax
,
pericardial effusion
,
pleural diseases
,
pleural neoplasms
,
hemothorax
,
procedural pain
,
cystic fibrosis
,
intravenous anesthesia
,
inhalation anesthesia
,
coronary artery disease
,
analgesia
,
glaucoma
,
conduction anesthesia
,
renal insufficiency
,
acute kidney injury
,
delirium
,
psychomotor agitation
,
hernia
,
depressive disorder
,
vascular diseases
,
heart diseases
,
obstetric labor complications
,
pregnancy rate
,
coronary disease
,
myocardial ischemia
,
angina pectoris
,
vasovagal syncope
,
syncope
,
hysterectomy
,
diabetic retinopathy
,
conjunctivitis
,
retinal neovascularization
,
pathologic neovascularization
,
carotid stenosis
,
aortic dissection
,
thoracic surgical procedures
,
cardiac catheterization
,
blood coagulation tests
,
postoperative cognitive complications
,
morbid obesity
,
diaphragmatic hernias congenital
,
diaphragmatic hernia
,
hypersensitivity
,
urinary bladder neoplasms
,
cardiovascular diseases
,
sudden death cardiac
,
radiotherapy
,
obesity
,
myalgia
,
common cold
,
irritable bowel syndrome
,
gastrointestinal diseases
,
dyspepsia
,
abdominal pain
,
pancreatitis
,
stress echocardiography
,
diastolic heart failure
,
interstitial lung diseases
,
respiratory signs and symptoms
,
exercise
,
quadriplegia
,
acute lung injury
,
thoracotomy
,
critical care
,
bronchitis
,
cough
,
psychology biofeedback
,
hypertension
,
drug overdose
,
suicide
,
prosthesis failure
,
confusion
,
aging
,
polymorphic catecholaminergic ventricular tachycardia
,
postural orthostatic tachycardia syndrome
,
fissure in ano
,
hemorrhoids
,
noise
,
gastric outlet obstruction
,
oculocardiac reflex
,
bronchiectasis
,
airway remodeling
,
airway obstruction
,
exotropia
,
microvascular angina
,
variant angina pectoris
,
thoracic diseases
,
local anesthesia
,
postoperative complications
,
inguinal hernia
,
rhinoplasty
,
esthetics
,
systolic murmurs
,
atrioventricular block
,
major depressive disorder
,
sick sinus syndrome
,
supraventricular tachycardia
,
brain hypoxia
,
pregnancy complications
,
myasthenia gravis
,
aortic aneurysm
,
ophthalmologic surgical procedures
,
bariatric surgery
,
projection
,
atrial fibrillation
,
deep sedation
,
urinary retention
,
costus
,
cholecystitis
,
intraocular pressure
,
infections
,
communicable diseases
,
unconsciousness
,
nasal surgical procedures
Anthracycline
neoplasm metastasis
,
leiomyosarcoma
,
fibrosarcoma
,
liposarcoma
,
hemangiosarcoma
,
synovial sarcoma
,
rhabdomyosarcoma
,
neurofibrosarcoma
,
malignant fibrous histiocytoma
,
nerve sheath neoplasms
,
myelodysplastic syndromes
,
lymphoid leukemia
,
myeloid leukemia
,
thrombocytopenia
,
lymphoma
,
mantle-cell lymphoma
,
bcr-abl positive chronic myelogenous leukemia
,
heart failure
,
male breast neoplasms
,
breast neoplasms
,
myeloid leukemia acute
,
leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
sarcoma
,
congenital abnormalities
,
brain neoplasms
,
lobular carcinoma
,
ductal carcinoma breast
,
megakaryoblastic leukemia acute
,
monocytic leukemia acute
,
myelomonocytic leukemia acute
,
basophilic leukemia acute
,
erythroblastic leukemia acute
,
eosinophilic leukemia acute
,
multiple myeloma
,
osteosarcoma
,
ovarian neoplasms
,
fallopian tube neoplasms
,
peritoneal neoplasms
,
recurrence
,
follicular lymphoma
Endocrine
renal cell carcinoma
,
carcinoma
,
non-small-cell lung carcinoma
,
endometrial neoplasms
,
hepatocellular carcinoma
,
stomach neoplasms
,
melanoma
,
liver neoplasms
,
mesothelioma
,
gastrointestinal neoplasms
,
neuroendocrine tumors
,
type 2 diabetes mellitus
,
diabetes mellitus
,
hypertension
,
glucose metabolism disorders
,
metabolic diseases
,
endocrine system diseases
,
breast neoplasms
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