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Puma Biotechnology
Puma Biotechnology
(PBYI)
Puma Biotechnology is a publicly traded biopharmaceutical company (NASDAQ: PBYI) headquartered in Los Angeles, CA.
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Nerlynx
Neratinib
2017-07-17
2025-2031
Breast neoplasms
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Neratinib
breast neoplasms
,
biliary tract neoplasms
,
neoadjuvant therapy
Benzimidazole
mantle-cell lymphoma
,
type 2 diabetes mellitus
,
diabetes mellitus
,
weight loss
,
b-cell lymphoma
,
large b-cell lymphoma diffuse
,
b-cell chronic lymphocytic leukemia
,
lymphoma
,
leukemia
,
lymphoid leukemia
,
non-hodgkin lymphoma
,
follicular lymphoma
Aglatimagene besadenovec
breast neoplasms
,
ovarian neoplasms
,
non-small-cell lung carcinoma
,
stomach neoplasms
,
head and neck neoplasms
,
esophageal neoplasms
,
lung neoplasms
,
urinary bladder neoplasms
,
small cell lung carcinoma
,
endophthalmitis
,
lacrimal apparatus diseases
,
lacerations
,
nocturia
,
prostatic hyperplasia
,
hyperplasia
,
overactive urinary bladder
,
prostatic neoplasms
Alisertib
pancreatic ductal carcinoma
,
pancreatic neoplasms
,
neoplasms
,
acinar cell carcinoma
,
myeloid leukemia acute
Edrecolomab
anemia
,
anxiety disorders
,
depressive disorder
,
heart failure
,
hepatitis b
,
hepatitis
,
hepatitis a
,
multiple myeloma
,
plasma cell neoplasms
,
chronic hepatitis b
,
human influenza
,
chronic hepatitis
,
infections
,
urinary tract infections
,
restless legs syndrome
,
psychomotor agitation
,
syndrome
Lornoxicam
leukemia
,
non-hodgkin lymphoma
,
lymphoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
cerebrotendinous xanthomatosis
,
xanthomatosis
Aspartame
tuberculosis
,
neoplasms
,
myeloid leukemia acute
,
deficiency diseases
,
paraproteinemias
,
hiv infections
,
precursor cell lymphoblastic leukemia-lymphoma
,
breast neoplasms
,
immune system diseases
,
hematologic neoplasms
,
type 2 diabetes mellitus
,
uveitis
,
metabolic diseases
,
disease
,
glycogen storage disease
,
lipidoses
,
immunoglobulin g4-related disease
,
leukemia
,
myeloid leukemia
,
malaria
,
falciparum malaria
,
whooping cough
,
tetanus
,
diphtheria
,
tetany
,
polycystic kidney diseases
,
autosomal dominant polycystic kidney
,
arthrogryposis
,
renal insufficiency
,
hematologic diseases
,
blood protein disorders
,
neoplasms by histologic type
,
prostatic neoplasms
,
circulating neoplastic cells
,
x-linked bulbo-spinal atrophy
,
heart transplantation
,
non-small-cell lung carcinoma
,
nasopharyngeal carcinoma
,
nasopharyngeal neoplasms
,
esophageal neoplasms
,
adenocarcinoma
,
neoplasm metastasis
,
aplastic anemia
,
multiple myeloma
,
plasma cell neoplasms
,
hypercholesterolemia
,
meningococcal infections
,
hemolytic anemia autoimmune
,
meningitis
,
meningococcal meningitis
,
stomach neoplasms
,
hemophilia a
,
kidney diseases
,
gaucher disease
,
smoldering multiple myeloma
,
hemophilia b
,
chronic renal insufficiency
,
hyperphosphatemia
,
multiple sclerosis
,
sclerosis
,
homozygous familial hypercholesterolemia
,
hyperlipoproteinemia type ii
,
pharyngitis
,
tonsillitis
,
healthy volunteers/patients
,
asthma
,
glycogen storage disease type ii
,
atopic dermatitis
,
diabetes mellitus
,
insulin resistance
,
hyperglycemia
,
glycogen storage disease type iii
,
heartburn
,
non-hodgkin lymphoma
,
osteoporosis
,
postmenopausal osteoporosis
,
lymphoma
,
lymphoproliferative disorders
Bevifimod
pancreatic neoplasms
,
type 2 diabetes mellitus
,
recurrence
,
renal cell carcinoma
,
carcinoma
,
colorectal neoplasms
,
neoplasms
,
mantle-cell lymphoma
,
rectal neoplasms
,
adenocarcinoma
,
chronic hepatitis c
,
lung neoplasms
,
brain neoplasms
,
squamous cell carcinoma of head and neck
,
cytokine release syndrome
,
neurotoxicity syndromes
,
syndrome
,
large b-cell lymphoma diffuse
,
colonic neoplasms
,
kidney diseases
,
membranous glomerulonephritis
,
chronic hepatitis b
,
mycoses
,
hematopoietic stem cell transplantation
,
male breast neoplasms
,
skin neoplasms
,
mouth neoplasms
,
oropharyngeal neoplasms
,
laryngeal neoplasms
,
hypopharyngeal neoplasms
,
lymphoma
,
b-cell chronic lymphocytic leukemia
,
non-hodgkin lymphoma
,
non-small-cell lung carcinoma
,
b-cell lymphoma
,
breast neoplasms
,
acquired immunodeficiency syndrome
,
follicular lymphoma
,
hepatitis c
,
triple negative breast neoplasms
,
hiv
,
leukemia
,
lymphoid leukemia
,
b-cell lymphoma marginal zone
,
waldenstrom macroglobulinemia
,
cystic fibrosis
,
pseudomonas infections
,
rheumatoid arthritis
,
infections
,
hepatitis b
,
communicable diseases
,
hepatitis
,
hepatitis a
,
psoriatic arthritis
,
covid-19
,
coronavirus infections
,
severe acute respiratory syndrome
,
virus diseases
,
coronaviridae infections
,
nidovirales infections
,
rna virus infections
,
stomach neoplasms
,
hiv infections
,
b-cell leukemia
Doxecitine
non-hodgkin lymphoma
,
follicular lymphoma
,
large b-cell lymphoma diffuse
,
triple negative breast neoplasms
,
thymoma
,
gastrointestinal neoplasms
,
neoplasms
,
pancreatic neoplasms
,
cholangiocarcinoma
,
hepatocellular carcinoma
,
liver neoplasms
,
colorectal neoplasms
,
bile duct neoplasms
,
digestive system neoplasms
,
gastrointestinal stromal tumors
,
gallbladder neoplasms
,
adenocarcinoma
,
stomach neoplasms
,
biliary tract neoplasms
,
extranodal nk-t-cell lymphoma
,
t-cell lymphoma peripheral
,
ductal carcinoma
,
transitional cell carcinoma
,
urinary bladder diseases
,
neoplasm metastasis
,
urinary bladder neoplasms
,
breast neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
carcinoma
,
renal cell carcinoma
Nepidermin
laron syndrome
,
pituitary dwarfism
,
glioblastoma
,
breast neoplasms
,
mucinous adenocarcinoma
,
ductal carcinoma breast
,
inflammatory breast neoplasms
,
parkinson disease
,
leukemia
,
promyelocytic leukemia acute
,
carcinoma
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
progressive supranuclear palsy
,
paralysis
Polyglycolic acid
carcinoma
,
hepatocellular carcinoma
,
liver neoplasms
,
pancreatic neoplasms
Globulin, immune
healthy volunteers/patients
,
bcr-abl positive chronic myelogenous leukemia
,
acquired immunodeficiency syndrome
,
hepatitis c
,
hepatitis
,
hepatitis a
,
glandular and epithelial neoplasms
,
myoepithelioma
,
gata2 deficiency
,
hiv-2
,
fallopian tube diseases
,
sepsis
,
bronchiolitis obliterans syndrome
,
atopic dermatitis
,
eczema
,
dermatitis
,
myeloproliferative disorders
,
nerve sheath neoplasms
,
neoplasms by histologic type
,
adenosquamous carcinoma
,
astrocytoma
,
central nervous system neoplasms
,
vitiligo
,
behcet syndrome
,
relapsing polychondritis
,
myasthenia gravis
,
mouth neoplasms
,
hiv infections
,
immunosuppression therapy
,
pancreatic neoplasms
,
transitional cell carcinoma
,
urologic neoplasms
,
lymphoma
,
ovarian neoplasms
,
squamous cell carcinoma
,
sarcoma
,
leukemia
,
b-cell chronic lymphocytic leukemia
,
plasma cell neoplasms
,
malignant mesothelioma
,
biliary tract neoplasms
,
large b-cell lymphoma diffuse
,
glioma
,
uterine cervical neoplasms
,
endometrial neoplasms
,
castration-resistant prostatic neoplasms
,
pancreatic ductal carcinoma
,
uveal neoplasms
,
uveal melanoma
,
hematologic neoplasms
,
neoplasms by site
,
myeloid leukemia acute
,
squamous cell neoplasms
,
follicular lymphoma
,
microsatellite instability
,
t-cell lymphoma
,
graft vs host disease
,
b-cell lymphoma
,
neuroendocrine tumors
,
myelodysplastic syndromes
,
mantle-cell lymphoma
,
t-cell lymphoma peripheral
,
colitis
,
ulcer
,
chordoma
,
gastrointestinal neoplasms
,
adenocarcinoma of lung
,
cholangiocarcinoma
,
lymphoid leukemia
,
myeloid leukemia
,
interstitial lung diseases
,
urogenital neoplasms
,
merkel cell carcinoma
,
spinocerebellar degenerations
,
laryngeal diseases
,
laryngitis
,
osteosarcoma
,
psychology rejection
,
smoldering multiple myeloma
,
clear cell adenocarcinoma
,
nose neoplasms
,
neuroblastoma
,
ewing sarcoma
,
rhabdomyosarcoma
,
b-cell leukemia
,
b-cell lymphoma marginal zone
,
nasopharyngeal carcinoma
,
nasopharyngeal neoplasms
,
prostatic diseases
,
penile neoplasms
,
gliosarcoma
,
autoimmune diseases
,
multiple sclerosis
,
waldenstrom macroglobulinemia
,
extranodal nk-t-cell lymphoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
burkitt lymphoma
,
female genital neoplasms
,
hypersensitivity
,
peritoneal neoplasms
,
salivary gland neoplasms
,
endometrioid carcinoma
,
leiomyosarcoma
,
carcinosarcoma
,
organ transplantation
,
neuroendocrine carcinoma
,
urinary bladder diseases
,
carcinoid tumor
,
basal cell carcinoma
,
basal cell neoplasms
,
diffuse scleroderma
,
kaposi sarcoma
,
heart transplantation
,
plant tumors
,
male breast neoplasms
,
meningioma
,
medulloblastoma
,
ependymoma
,
tertiary lymphoid structures
,
oropharyngeal neoplasms
,
fowlpox
,
non-muscle invasive bladder neoplasms
,
diffuse intrinsic pontine glioma
,
sars-cov-2
,
nephrotic syndrome
,
focal segmental glomerulosclerosis
,
lipoid nephrosis
,
common variable immunodeficiency
,
male genital neoplasms
,
large-cell lymphoma anaplastic
,
rhabdoid tumor
,
phenylketonurias
,
bile duct neoplasms
,
serous cystadenocarcinoma
,
papillary thyroid cancer
,
myositis
,
genetic therapy
,
uterine neoplasms
,
large cell carcinoma
,
endometrial stromal tumors
,
small cell carcinoma
,
adrenocortical carcinoma
,
thoracic neoplasms
,
thymoma
,
thymus neoplasms
,
digestive system diseases
,
hypertension
,
inflammation
,
hepatoblastoma
,
wilms tumor
,
proteinuria
,
invasive hydatidiform mole
,
pruritus
,
exanthema
,
urticaria
,
aggression
,
bronchiolo-alveolar adenocarcinoma
,
drug-related side effects and adverse reactions
,
thyroid neoplasms
,
precancerous conditions
,
bronchopulmonary dysplasia
,
tobacco smoking
,
meningeal carcinomatosis
,
systemic scleroderma
,
patient preference
,
uveitis
,
oral leukoplakia
,
germ cell and embryonal neoplasms
,
churg-strauss syndrome
,
microscopic polyangiitis
,
asthma
,
oligodendroglioma
,
preleukemia
,
syndrome
,
ankylosing spondylitis
,
motor activity
,
alopecia areata
,
inflammatory breast neoplasms
,
cerebral palsy
,
sarcoidosis
,
gastrointestinal stromal tumors
,
male urogenital diseases
,
female urogenital diseases
,
female urogenital diseases and pregnancy complications
,
urogenital diseases
,
reactive arthritis
,
alzheimer disease
,
hereditary nonpolyposis colorectal neoplasms
,
disease
,
melanoma
,
neoplasms
,
colorectal neoplasms
,
neoplasm metastasis
,
squamous cell carcinoma of head and neck
,
prostatic neoplasms
,
breast neoplasms
,
liver neoplasms
,
head and neck neoplasms
,
adenocarcinoma
,
multiple myeloma
,
hepatocellular carcinoma
,
urinary bladder neoplasms
,
carcinoma
,
stomach neoplasms
,
recurrence
,
hodgkin disease
,
small cell lung carcinoma
,
brain neoplasms
,
colonic neoplasms
,
non-hodgkin lymphoma
,
triple negative breast neoplasms
,
rectal neoplasms
,
glioblastoma
,
esophageal neoplasms
,
skin neoplasms
,
cutaneous malignant melanoma
,
ulcerative colitis
,
fallopian tube neoplasms
,
psoriasis
,
mesothelioma
,
systemic lupus erythematosus
,
ovarian epithelial carcinoma
,
sjogren's syndrome
,
esophageal squamous cell carcinoma
,
crohn disease
,
juvenile arthritis
,
covid-19
,
coronavirus infections
,
immunoglobulin g4-related disease
,
lupus nephritis
,
giant cell arteritis
,
lung diseases
,
granulomatosis with polyangiitis
,
anti-neutrophil cytoplasmic antibody-associated vasculitis
,
polymyalgia rheumatica
,
nephritis
,
respiratory tract diseases
,
vascular diseases
,
vasculitis
,
systemic vasculitis
,
disease progression
,
pathologic complete response
,
coronavirus
,
arthralgia
,
non-small-cell lung carcinoma
,
rheumatoid arthritis
,
renal cell carcinoma
,
lung neoplasms
,
kidney transplantation
,
kidney neoplasms
,
arthritis
,
graft rejection
,
psoriatic arthritis
,
delayed graft function
,
chronic kidney failure
,
transplantation
,
myocarditis
,
epstein-barr virus infections
,
ischemia
,
coronary artery disease
,
spondylarthritis
,
spondylitis
,
biliary liver cirrhosis
,
lymphocytosis
,
encephalitis
,
necrosis
,
cardiomyopathies
,
dilated cardiomyopathy
,
type 1 diabetes mellitus
,
islets of langerhans transplantation
Digitalis
healthy volunteers/patients
Hyoscyamine
newborn respiratory distress syndrome
Anthracycline
neoplasms
,
neoplasms by histologic type
,
connective and soft tissue neoplasms
,
breast neoplasms
,
ovarian neoplasms
,
ovarian epithelial carcinoma
,
myeloid leukemia acute
,
plasmablastic lymphoma
,
large-cell lymphoma immunoblastic
,
leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
,
t-cell lymphoma
,
t-cell lymphoma peripheral
,
lymphoma
,
b-cell lymphoma
,
multiple myeloma
,
plasma cell neoplasms
,
leiomyosarcoma
,
large b-cell lymphoma diffuse
,
sarcoma
,
liposarcoma
,
non-hodgkin lymphoma
,
b-cell lymphoma marginal zone
,
follicular lymphoma
,
mantle-cell lymphoma
,
carcinoma
,
hepatocellular carcinoma
,
liver neoplasms
,
circulating neoplastic cells
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