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Puma Biotechnology
Puma Biotechnology
(PBYI)
Puma Biotechnology is a publicly traded biopharmaceutical company (NASDAQ: PBYI) headquartered in Los Angeles, CA.
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Therapeutic Areas:
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Nerlynx
Neratinib
2017-07-17
2025-2031
Breast neoplasms
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Neratinib
healthy volunteers/patients
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
hematologic neoplasms
,
pancreatic neoplasms
,
myeloproliferative disorders
,
non-hodgkin lymphoma
,
primary myelofibrosis
,
multiple myeloma
,
precursor cell lymphoblastic leukemia-lymphoma
,
b-cell chronic lymphocytic leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
myelomonocytic leukemia chronic
,
anemia
,
hodgkin disease
,
leukemia myeloid chronic atypical bcr-abl negative
,
myelodysplastic-myeloproliferative diseases
,
plasma cell neoplasms
,
myeloid leukemia chronic-phase
,
myeloid leukemia
,
myeloid leukemia accelerated phase
,
myelomonocytic leukemia juvenile
,
preleukemia
,
blast crisis
,
thrombocytosis
,
syndrome
,
lymphoid leukemia
,
erbb-2 genes
,
erbb genes
,
ovarian epithelial carcinoma
,
liver failure
,
hepatic insufficiency
,
esophageal neoplasms
,
gastrointestinal neoplasms
,
neoplasms
,
neoplasm metastasis
,
triple negative breast neoplasms
,
brain neoplasms
,
adenocarcinoma
,
carcinoma
,
diarrhea
,
non-small-cell lung carcinoma
,
stomach neoplasms
,
leukemia
,
prostatic neoplasms
,
castration-resistant prostatic neoplasms
,
lymphoma
,
colorectal neoplasms
,
lung neoplasms
,
ovarian neoplasms
,
inflammatory breast neoplasms
,
female genital neoplasms
,
neurofibromatosis 2
,
acoustic neuroma
,
meningioma
,
ependymoma
,
neurofibromatosis 1
,
neurofibromatoses
,
neurofibroma
,
neurilemmoma
,
hemangiosarcoma
,
glioblastoma
,
central nervous system neoplasms
,
nervous system neoplasms
,
endometrial neoplasms
,
fallopian tube neoplasms
,
lobular carcinoma
,
invasive hydatidiform mole
,
pancreatic ductal carcinoma
,
ductal carcinoma
,
myoepithelioma
,
breast neoplasms
,
recurrence
,
biliary tract neoplasms
,
uterine cervical neoplasms
,
urinary bladder neoplasms
,
neoadjuvant therapy
Fam-trastuzumab deruxtecan-nxki
neoplasms
Ado-trastuzumab emtansine
neoplasms
,
non-small-cell lung carcinoma
,
triple negative breast neoplasms
,
neoplasm metastasis
,
pancreatic neoplasms
,
urinary bladder neoplasms
,
cholangiocarcinoma
,
lung neoplasms
,
ovarian neoplasms
,
stomach neoplasms
,
residual neoplasm
,
recurrence
,
inflammatory breast neoplasms
,
breast neoplasms
Albumin
triple negative breast neoplasms
,
renal cell carcinoma
,
malignant mesothelioma
,
mesothelioma
,
breast neoplasms
,
carcinoma
,
non-small-cell lung carcinoma
,
lung neoplasms
,
neoplasms
,
mucinous adenocarcinoma
,
ductal carcinoma breast
,
inflammatory breast neoplasms
,
head and neck neoplasms
,
respiratory tract diseases
,
germ cell and embryonal neoplasms
,
small cell lung carcinoma
,
lung diseases
,
respiratory tract neoplasms
,
bronchogenic carcinoma
,
thoracic neoplasms
,
adenocarcinoma
,
bronchial diseases
,
neoplasms by histologic type
,
neoplasms by site
,
nerve tissue neoplasms
Antithrombin iii
anemia
,
iron-deficiency anemia
,
iron deficiencies
,
deficiency diseases
,
chronic renal insufficiency
,
kidney diseases
Aglatimagene besadenovec
prostatic neoplasms
,
castration-resistant prostatic neoplasms
,
breast neoplasms
,
ovarian neoplasms
Alisertib
head and neck neoplasms
,
gastrointestinal neoplasms
,
digestive system neoplasms
,
pancreatic neoplasms
,
b-cell chronic lymphocytic leukemia
,
colorectal neoplasms
,
mucinous adenocarcinoma
,
colonic neoplasms
,
rectal neoplasms
,
cystadenocarcinoma
,
urogenital neoplasms
,
central nervous system neoplasms
,
thoracic neoplasms
,
mycoses
,
sezary syndrome
,
mycosis fungoides
,
hairy cell leukemia
,
intraocular lymphoma
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
plasmablastic lymphoma
,
large granular lymphocytic leukemia
,
large-cell lymphoma immunoblastic
,
lymphomatoid granulomatosis
,
lymphoid leukemia
,
hematologic neoplasms
,
enteropathy-associated t-cell lymphoma
,
female genital neoplasms
,
lip neoplasms
,
male genital neoplasms
,
papilloma
,
triple negative breast neoplasms
,
brain neoplasms
,
glioblastoma
,
glioma
,
gliosarcoma
,
ependymoma
,
astrocytoma
,
oligodendroglioma
,
pancreatic ductal carcinoma
,
acinar cell carcinoma
,
neoplasms
,
recurrence
,
breast neoplasms
,
mantle-cell lymphoma
,
b-cell lymphoma
,
adenocarcinoma
,
lung neoplasms
,
non-hodgkin lymphoma
,
follicular lymphoma
,
large b-cell lymphoma diffuse
,
burkitt lymphoma
,
leukemia
,
prostatic neoplasms
,
carcinoma
,
small cell lung carcinoma
,
myeloid leukemia acute
,
non-small-cell lung carcinoma
,
neuroblastoma
,
ovarian neoplasms
,
hodgkin disease
,
b-cell lymphoma marginal zone
,
waldenstrom macroglobulinemia
,
large-cell lymphoma anaplastic
,
immunoblastic lymphadenopathy
,
myeloid leukemia
,
multiple myeloma
,
melanoma
,
squamous cell carcinoma of head and neck
,
precursor cell lymphoblastic leukemia-lymphoma
,
adult t-cell leukemia-lymphoma
,
t-cell lymphoma cutaneous
,
t-cell leukemia
,
sarcoma
,
leiomyosarcoma
,
plasma cell neoplasms
,
invasive hydatidiform mole
,
postmenopause
,
teratoma
,
rhabdoid tumor
,
phenylketonurias
,
squamous cell carcinoma
,
urinary bladder neoplasms
,
transitional cell carcinoma
,
fallopian tube neoplasms
,
peritoneal neoplasms
,
malignant mesothelioma
,
mesothelioma
,
myelodysplastic syndromes
,
preleukemia
,
syndrome
,
fibrosarcoma
,
liposarcoma
,
neurofibrosarcoma
,
malignant fibrous histiocytoma
,
nerve sheath neoplasms
,
extranodal nk-t-cell lymphoma
,
osteosarcoma
,
kidney neoplasms
,
ewing sarcoma
,
rhabdomyosarcoma
,
primitive neuroectodermal tumors
,
primitive neuroectodermal tumors peripheral
,
hepatoblastoma
,
embryonal rhabdomyosarcoma
,
neuroectodermal tumors
,
lymphoma
,
t-cell lymphoma
,
t-cell lymphoma peripheral
,
primary myelofibrosis
,
megakaryoblastic leukemia acute
Edrecolomab
leukemia
,
non-hodgkin lymphoma
,
lymphoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
lymphoid leukemia
Lornoxicam
non-hodgkin lymphoma
,
lymphoma
,
myelodysplastic syndromes
,
myeloproliferative disorders
,
primary myelofibrosis
,
promyelocytic leukemia acute
,
bcr-abl positive chronic myelogenous leukemia
,
myelomonocytic leukemia chronic
,
myelomonocytic leukemia acute
,
myelomonocytic leukemia juvenile
,
preleukemia
,
acute disease
,
lymphoid leukemia
,
b-cell lymphoma
,
leukemia
,
myeloid leukemia acute
,
precursor cell lymphoblastic leukemia-lymphoma
,
myeloid leukemia
,
recurrence
,
diabetes mellitus
,
type 1 diabetes mellitus
,
breast neoplasms
,
glycogen storage disease type ii
,
glycogen storage disease type iii
,
glycogen storage disease
,
ovarian neoplasms
Aspartame
hiv
,
bronchiectasis
,
escherichia coli infections
,
gastroenteritis
,
pharmacokinetics
,
dental plaque
,
hydrogen-ion concentration
,
salivation
,
healthy volunteers/patients
,
xerostomia
,
sjogren's syndrome
,
ototoxicity
,
mucositis
,
glioblastoma
,
pyruvate dehydrogenase complex deficiency disease
,
covid-19
,
sepsis
,
malnutrition
,
child nutrition disorders
,
colonoscopy
,
obesity
,
type 2 diabetes mellitus
,
overweight
,
diabetes mellitus
,
insulin resistance
,
glucose intolerance
,
body weight
,
metabolic syndrome
,
weight loss
,
feeding behavior
,
glucose metabolism disorders
,
metabolic diseases
,
abdominal obesity
,
adiposity
,
dyslipidemias
,
prediabetic state
,
glucose tolerance test
,
cognition
,
fasting
,
type 1 diabetes mellitus
,
placebos
,
hypoglycemia
,
gastric bypass
,
congenital hyperinsulinism
,
nesidioblastosis
,
driving under the influence
,
glycogen storage disease type iii
,
glycogen storage disease
,
kidney transplantation
,
hyperglycemia
,
sleep deprivation
,
cardiovascular diseases
,
mortality
,
hypersensitivity
,
gastrointestinal microbiome
,
chronic disease
,
neoplasms
,
diet
,
adolescent development
,
acromegaly
,
appetitive behavior
,
microbiota
,
chronic periodontitis
,
periodontitis
,
thirst
,
pregnancy rate
,
atherosclerosis
,
appetite
,
intestinal absorption
,
taste
,
hypoxia
,
blood glucose self-monitoring
,
deglutition disorders
,
syndrome
,
thrombosis
,
inflammation
,
platelet aggregation
,
wounds and injuries
,
spinal cord injuries
,
cold temperature
,
sleep
,
blood pressure
,
vascular stiffness
,
aging
,
exercise tolerance
,
alcohol drinking
,
polycystic ovary syndrome
Bevifimod
non-small-cell lung carcinoma
,
lung neoplasms
Nepidermin
ulcerative colitis
,
colitis
,
ulcer
Polyglycolic acid
t-cell lymphoma cutaneous
,
mycoses
,
sezary syndrome
,
large-cell lymphoma anaplastic
,
primary cutaneous anaplastic large cell lymphoma
,
mycosis fungoides
,
non-hodgkin lymphoma
,
lymphoma
,
t-cell lymphoma
,
t-cell lymphoma peripheral
,
mucositis
,
hematologic neoplasms
,
breast neoplasms
,
carcinoma
,
urinary bladder neoplasms
,
transitional cell carcinoma
,
neoplasms
,
hodgkin disease
,
waldenstrom macroglobulinemia
,
b-cell lymphoma
Retinol
carcinoma
,
breast neoplasms
,
psoriasis
,
pancreatic ductal carcinoma
,
renal cell carcinoma
,
ovarian neoplasms
,
melanoma
,
hepatocellular carcinoma
,
liver neoplasms
,
glioma
,
healthy volunteers/patients
,
lung neoplasms
,
neoplasm metastasis
,
prostatic neoplasms
,
stomach neoplasms
,
esophageal neoplasms
,
hypocalcemia
,
rectal neoplasms
,
colorectal neoplasms
,
neoplasms
,
non-small-cell lung carcinoma
,
pancreatic neoplasms
,
adenocarcinoma
,
head and neck neoplasms
,
postmenopausal osteoporosis
,
osteoporosis
,
rheumatoid arthritis
,
arthritis
,
hip fractures
,
bone fractures
Hyoscyamine
general anesthesia
,
replacement arthroplasty knee
,
replacement arthroplasty hip
,
hip fractures
,
blood coagulation
,
neuromuscular blockade
,
delayed emergence from anesthesia
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