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Company ReportsPuma Biotechnology

Puma Biotechnology(PBYI)

Puma Biotechnology is a publicly traded biopharmaceutical company (NASDAQ: PBYI) headquartered in Los Angeles, CA.

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Clinical Trials

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Revenue by Drug

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Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Nerlynx	Neratinib	2017-07-17	2025-2031	Breast neoplasms

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

hematologic neoplasms

,

pancreatic neoplasms

,

myeloproliferative disorders

,

non-hodgkin lymphoma

,

primary myelofibrosis

,

multiple myeloma

,

precursor cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

bcr-abl positive chronic myelogenous leukemia

,

myelomonocytic leukemia chronic

,

,

hodgkin disease

,

leukemia myeloid chronic atypical bcr-abl negative

,

myelodysplastic-myeloproliferative diseases

,

plasma cell neoplasms

,

myeloid leukemia chronic-phase

,

myeloid leukemia

,

myeloid leukemia accelerated phase

,

myelomonocytic leukemia juvenile

,

,

,

,

,

lymphoid leukemia

,

,

,

ovarian epithelial carcinoma

,

,

hepatic insufficiency

,

esophageal neoplasms

,

,

neoplasm metastasis

,

triple negative breast neoplasms

,

brain neoplasms

,

,

,

non-small-cell lung carcinoma

,

stomach neoplasms

,

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

,

,

colorectal neoplasms

,

,

ovarian neoplasms

,

inflammatory breast neoplasms

,

female genital neoplasms

,

neurofibromatosis 2

,

acoustic neuroma

,

,

,

neurofibromatosis 1

,

neurofibromatoses

,

,

,

hemangiosarcoma

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

endometrial neoplasms

,

fallopian tube neoplasms

,

lobular carcinoma

,

invasive hydatidiform mole

,

breast neoplasms

,

,

biliary tract neoplasms

,

uterine cervical neoplasms

,

urinary bladder neoplasms

,

neoadjuvant therapy

Fam-trastuzumab deruxtecan-nxki

stomach neoplasms

,

esophageal neoplasms

Ado-trastuzumab emtansine

breast neoplasms

,

brain neoplasms

Aglatimagene besadenovec

,

,

head and neck neoplasms

,

esophageal neoplasms

,

disease progression

,

castration-resistant prostatic neoplasms

,

,

,

large b-cell lymphoma diffuse

,

urogenital neoplasms

,

male genital diseases

,

prostatic diseases

,

abdominal neoplasms

,

male genital neoplasms

,

genital diseases

,

,

myelomonocytic leukemia chronic

,

systemic mastocytosis

,

myelomonocytic leukemia juvenile

,

hypereosinophilic syndrome

,

,

dermatofibrosarcoma

,

hematologic neoplasms

,

,

,

small cell lung carcinoma

,

b-cell lymphoma

,

neuroendocrine tumors

,

urologic neoplasms

,

,

,

,

,

bone resorption

,

,

,

prostatic neoplasms

,

neoplasm metastasis

,

breast neoplasms

,

,

bone marrow diseases

,

multiple myeloma

,

second primary neoplasms

,

plasma cell neoplasms

,

hypersensitivity

,

,

pancreatic ductal carcinoma

,

pancreatic neoplasms

,

,

,

acinar cell carcinoma

,

,

myeloid leukemia acute

,

myeloid leukemia

healthy volunteers/patients

,

,

pituitary dwarfism

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

myelomonocytic leukemia acute

,

myeloid leukemia

,

erythroblastic leukemia acute

,

,

,

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

healthy volunteers/patients

,

hepatic insufficiency

,

esophageal neoplasms

,

,

,

small cell lung carcinoma

,

pancreatic ductal carcinoma

,

multiple myeloma

,

plasma cell neoplasms

,

bronchiolitis obliterans syndrome

,

congenital abnormalities

,

chromosome aberrations

,

brain stem neoplasms

,

chronic hepatitis c

,

chronic hepatitis

,

,

,

medulloblastoma

,

,

,

choroid plexus neoplasms

,

primitive neuroectodermal tumors

,

,

,

neuroepithelial neoplasms

,

ganglioneuroblastoma

,

neuroectodermal tumors

,

phenylketonurias

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

nasopharyngeal carcinoma

,

ureteral neoplasms

,

pelvic neoplasms

,

adenoid cystic carcinoma

,

metabolic syndrome

,

follicular lymphoma

,

,

pancreatic neoplasms

,

kidney neoplasms

,

,

prostatic neoplasms

,

,

,

head and neck neoplasms

,

neurofibromatoses

,

,

liver neoplasms

,

,

,

neurofibromatosis 1

,

plexiform neurofibroma

,

systemic scleroderma

,

diffuse scleroderma

,

b-cell chronic lymphocytic leukemia

,

,

hematologic neoplasms

,

endometrial neoplasms

,

neuroendocrine carcinoma

,

central nervous system neoplasms

,

ovarian neoplasms

,

mantle-cell lymphoma

,

urinary bladder neoplasms

,

squamous cell carcinoma

,

uterine cervical neoplasms

,

myelodysplastic syndromes

,

non-hodgkin lymphoma

,

nervous system neoplasms

,

hypereosinophilic syndrome

,

systemic mastocytosis

,

,

uveal neoplasms

,

squamous cell carcinoma of head and neck

,

t-cell lymphoma

,

transitional cell carcinoma

,

primary myelofibrosis

,

,

graft vs host disease

,

adenocarcinoma of lung

,

diffuse intrinsic pontine glioma

,

disease progression

,

oligodendroglioma

,

neurofibromatosis 2

,

acoustic neuroma

,

,

hodgkin disease

,

islet cell carcinoma

,

hematologic diseases

,

myeloid leukemia accelerated phase

,

,

mast-cell leukemia

,

,

germ cell and embryonal neoplasms

,

,

anaplastic thyroid carcinoma

,

t-cell lymphoma peripheral

,

waldenstrom macroglobulinemia

,

castration-resistant prostatic neoplasms

,

,

cholangiocarcinoma

,

chronic disease

,

large-cell lymphoma anaplastic

,

plasma cell granuloma

,

,

,

,

,

gouty arthritis

,

endocrine gland neoplasms

,

,

urogenital neoplasms

,

male genital diseases

,

prostatic diseases

,

abdominal neoplasms

,

male genital neoplasms

,

genital diseases

,

sjogren's syndrome

,

retinitis pigmentosa

,

,

,

giant cell tumors

,

pigmented villonodular synovitis

,

giant cell tumor of tendon sheath

,

choroidal neovascularization

,

pathologic neovascularization

,

hemangioblastoma

,

von hippel-lindau disease

,

inflammatory breast neoplasms

,

invasive hydatidiform mole

,

multidrug-resistant tuberculosis

,

local neoplasm recurrence

,

t-cell lymphoma cutaneous

,

peutz-jeghers syndrome

,

acute coronary syndrome

,

st elevation myocardial infarction

,

malignant mesothelioma

,

,

type 1 diabetes mellitus

,

,

intestinal neoplasms

,

testicular neoplasms

,

,

brain stem infarctions

,

,

sturge-weber syndrome

,

klippel-trenaunay-weber syndrome

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

carcinoma in situ

,

breast diseases

,

multiple hamartoma syndrome

,

,

urologic neoplasms

,

fallopian tube neoplasms

,

t-cell leukemia

,

localized scleroderma

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia acute

,

myelomonocytic leukemia juvenile

,

,

,

ovarian epithelial carcinoma

,

sickle cell anemia

,

streptococcus agalactiae

,

colorectal neoplasms

,

myeloid leukemia acute

,

,

,

neoplasm metastasis

,

brain neoplasms

,

hepatocellular carcinoma

,

,

thyroid neoplasms

,

thyroid diseases

,

chronic urticaria

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

triple negative breast neoplasms

,

,

colonic neoplasms

,

,

carcinoid tumor

,

pulmonary arterial hypertension

,

familial primary pulmonary hypertension

,

,

gastrointestinal neoplasms

,

stomach neoplasms

,

rectal neoplasms

,

,

meningococcal meningitis

,

meningococcal infections

,

rheumatoid arthritis

,

organ transplantation

,

graft rejection

,

digestive system neoplasms

,

cutaneous malignant melanoma

,

,

lymphangioleiomyomatosis

,

lupus nephritis

,

,

hypersensitivity

,

peanut hypersensitivity

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

interstitial lung diseases

,

,

lung transplantation

,

malignant carcinoid syndrome

,

serotonin syndrome

,

food hypersensitivity

,

psoriatic arthritis

,

,

muscular atrophy

,

spinal muscular atrophy

,

,

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

chronic inducible urticaria

,

infectious skin diseases

,

bacterial skin diseases

,

,

,

myeloid leukemia

,

,

bcr-abl positive chronic myelogenous leukemia

,

breast neoplasms

,

,

,

non-small-cell lung carcinoma

,

renal cell carcinoma

,

,

kidney transplantation

,

philadelphia chromosome

,

lymphoid leukemia

,

neuroendocrine tumors

,

gastrointestinal stromal tumors

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

myeloid leukemia chronic-phase

,

liver transplantation

,

renal insufficiency

,

tuberous sclerosis

,

chronic kidney failure

,

heart transplantation

,

kidney diseases

,

islet cell adenoma

,

,

,

macular degeneration

,

,

,

,

autosomal dominant polycystic kidney

,

communicable diseases

,

polycystic kidney diseases

,

,

diabetes mellitus

,

tick-borne encephalitis

,

,

immunosuppression therapy

,

cytomegalovirus infections

,

,

large cell carcinoma

,

vascular diseases

,

,

,

vision disorders

,

,

type 2 diabetes mellitus

,

cross-sectional studies

,

,

polyomavirus infections

,

cryopyrin-associated periodic syndromes

,

polycythemia vera

,

,

,

systolic heart failure

,

myocardial infarction

,

,

,

inferior wall myocardial infarction

,

hodgkin disease

,

,

pancreatic neoplasms

,

pancreatic ductal carcinoma

,

,

colonic neoplasms

,

rectal neoplasms

,

carotid artery diseases

,

atherosclerosis

,

,

hematologic neoplasms

,

sezary syndrome

,

b-cell chronic lymphocytic leukemia

,

prolymphocytic leukemia t-cell

,

t-cell lymphoma

,

prolymphocytic leukemia

,

t-cell lymphoma peripheral

,

t-cell lymphoma cutaneous

,

prolymphocytic leukemia b-cell

,

renal cell carcinoma

,

kidney neoplasms

,

gastrointestinal neoplasms

,

biliary tract neoplasms

,

hypercholesterolemia

,

,

,

hyperlipidemias

,

,

colorectal neoplasms

,

hyperlipoproteinemias

,

postmenopausal osteoporosis

,

hyperlipoproteinemia type v

,

familial combined hyperlipidemia

,

stomach neoplasms

,

non-small-cell lung carcinoma

,

,

,

esophageal neoplasms

,

type 2 diabetes mellitus

,

diabetes mellitus

,

vitamin d deficiency

,

non-hodgkin lymphoma

,

,

esophageal squamous cell carcinoma

,

hyperlipoproteinemia type ii

,

,

,

,

cardiovascular diseases

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

peripheral arterial disease

,

peripheral vascular diseases

,

heart transplantation

,

polycystic ovary syndrome

,

,

,

atopic dermatitis

,

,

healthy volunteers/patients

,

prediabetic state

,

glucose intolerance

,

,

,

orthostatic intolerance

,

,

digestive system physiological phenomena

,

gastrointestinal motility

,

,

,

near-infrared spectroscopy

,

,

,

insulin resistance

,

,

vasoconstriction

,

allergic rhinitis

,

autonomic nervous system diseases

,

orthostatic hypotension

,

nervous system diseases

,

primary dysautonomias

,

,

,

spinal fractures

,

pharmacokinetics

,

breast neoplasms

,

,

non-small-cell lung carcinoma

,

brain neoplasms

,

,

colonic neoplasms

,

,

allergic rhinitis seasonal

,

,

,

alveolar soft part sarcoma

,

blood coagulation disorders

,

hemostatic disorders

,

,

,

granulosa cell tumor

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

regional blood flow

,

ocular physiological phenomena

,

ventilator-associated pneumonia

,

,

,

,

pancreatic neoplasms

,

ductal carcinoma

,

,

eye axial length

,

degenerative myopia

,

general anesthesia

,

emergence delirium

,

,

,

,

replacement arthroplasty hip

,

,

,

,

,

anterior uveitis

,

,

,

anesthesia and analgesia

,

,

stomach neoplasms

,

neoplasm metastasis

,

retinal diseases

,

retinopathy of prematurity

,

cerebral infarction

,

replacement arthroplasty knee

,

,

blood coagulation

,

,

colorectal neoplasms

,

,

neuromuscular blockade

,

,

,

,

postoperative pain

,

,

,

postoperative nausea and vomiting

,

,

,

delayed emergence from anesthesia

,

cesarean section

,

respiratory distress syndrome

,

newborn respiratory distress syndrome

,

organophosphate poisoning

,

drug-related side effects and adverse reactions

,

spinal anesthesia

,

intratracheal intubation

,

,

cognitive dysfunction

,

muscle hypotonia

,

,

,

,

,

post-dural puncture headache

,

cardiac arrhythmias

,

disease progression

,

retinal detachment

,

premature birth

,

,

,

,

obstructive sleep apnea

,

sleep apnea syndromes

,

,

respiratory insufficiency

,

,

,

,

wounds and injuries

,

hip osteoarthritis

,

refractive errors

,

,

pulmonary atelectasis

,

,

,

cholecystolithiasis

,

alzheimer disease

,

cognition disorders

,

neurocognitive disorders

,

postoperative period

,

anesthesia recovery period

,

,

liver cirrhosis

,

muscle relaxation

,

,

newborn infant diseases

,

dental care for disabled

,

,

nephrolithiasis

,

,

lower urinary tract symptoms

,

esophageal achalasia

,

conscious sedation

,

hepatocellular carcinoma

,

liver neoplasms

,

muscle weakness

,

myocardial infarction

,

,

,

inferior wall myocardial infarction

,

pleural effusion

,

,

,

malignant pleural effusion

,

lymphadenopathy

,

pleural empyema

,

,

,

pericardial effusion

,

pleural diseases

,

pleural neoplasms

,

,

procedural pain

,

cystic fibrosis

,

coronary artery disease

,

,

,

conduction anesthesia

,

psychomotor agitation

,

,

depressive disorder

,

intravenous anesthesia

,

vascular diseases

,

,

obstetric labor complications

,

,

coronary disease

,

myocardial ischemia

,

angina pectoris

,

,

vasovagal syncope

,

,

,

diabetic retinopathy

,

,

retinal neovascularization

,

pathologic neovascularization

,

carotid stenosis

,

aortic dissection

,

thoracic surgical procedures

,

renal insufficiency

,

cardiac catheterization

,

blood coagulation tests

,

postoperative cognitive complications

,

,

diaphragmatic hernias congenital

,

diaphragmatic hernia

,

urinary bladder neoplasms

,

cardiovascular diseases

,

sudden death cardiac

,

,

,

respiratory aspiration

,

inhalation anesthesia

,

,

,

irritable bowel syndrome

,

gastrointestinal diseases

,

,

,

digestive system diseases

,

,

stress echocardiography

,

diastolic heart failure

,

psychology biofeedback

,

,

,

,

prosthesis failure

,

,

,

ventricular tachycardia

,

postural orthostatic tachycardia syndrome

,

,

,

,

,

gastric outlet obstruction

,

oculocardiac reflex

,

,

,

microvascular angina

,

variant angina pectoris

,

thoracic diseases

,

local anesthesia

,

postoperative complications

,

inguinal hernia

,

,

,

systolic murmurs

,

atrioventricular block

,

,

major depressive disorder

,

sick sinus syndrome

,

supraventricular tachycardia

,

,

pregnancy complications

,

myasthenia gravis

,

aortic aneurysm

,

ophthalmologic surgical procedures

,

bariatric surgery

b-cell lymphoma

,

hodgkin disease

,

,

breast neoplasms

,

,

chemotherapy-induced febrile neutropenia

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

inflammatory breast neoplasms

,

non-hodgkin lymphoma

,

mantle-cell lymphoma

,

endocrine gland neoplasms

,

pheochromocytoma

,

,

neuroendocrine tumors

,

anaplastic thyroid carcinoma

,

,

,

lobular carcinoma

,

invasive hydatidiform mole

,

circulating neoplastic cells

,

breast neoplasms

,

diabetes mellitus

,

triple negative breast neoplasms

,

,

coronary artery disease

,

male breast neoplasms

b-cell lymphoma

,

hodgkin disease

,

,

breast neoplasms

,

,

chemotherapy-induced febrile neutropenia

,

mucinous adenocarcinoma

,

ductal carcinoma breast

,

inflammatory breast neoplasms

,

non-hodgkin lymphoma

,

mantle-cell lymphoma

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