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Puma Biotechnology
Puma Biotechnology
(PBYI)
Puma Biotechnology is a publicly traded biopharmaceutical company (NASDAQ: PBYI) headquartered in Los Angeles, CA.
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Nerlynx
Neratinib
2017-07-17
2025-2031
Breast neoplasms
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Neratinib
healthy volunteers/patients
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
hematologic neoplasms
,
pancreatic neoplasms
,
myeloproliferative disorders
,
non-hodgkin lymphoma
,
primary myelofibrosis
,
multiple myeloma
,
precursor cell lymphoblastic leukemia-lymphoma
,
b-cell chronic lymphocytic leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
myelomonocytic leukemia chronic
,
anemia
,
hodgkin disease
,
leukemia myeloid chronic atypical bcr-abl negative
,
myelodysplastic-myeloproliferative diseases
,
myeloid leukemia chronic-phase
,
myeloid leukemia accelerated phase
,
blast crisis
,
thrombocytosis
,
erbb-2 genes
,
erbb genes
,
ovarian epithelial carcinoma
,
liver failure
,
hepatic insufficiency
,
gastrointestinal neoplasms
,
esophageal squamous cell carcinoma
,
neoplasms
,
neoplasm metastasis
,
triple negative breast neoplasms
,
brain neoplasms
,
stomach neoplasms
,
non-small-cell lung carcinoma
,
adenocarcinoma
,
prostatic neoplasms
,
castration-resistant prostatic neoplasms
,
diarrhea
,
colorectal neoplasms
,
lung neoplasms
,
ovarian neoplasms
,
inflammatory breast neoplasms
,
neurofibromatosis 2
,
acoustic neuroma
,
meningioma
,
ependymoma
,
neurofibromatosis 1
,
neurofibromatoses
,
neurofibroma
,
neurilemmoma
,
hemangiosarcoma
,
hereditary sensory and autonomic neuropathies
,
carcinoma
,
glioblastoma
,
leukemia
,
lymphoma
,
central nervous system neoplasms
,
nervous system neoplasms
,
endometrial neoplasms
,
fallopian tube neoplasms
,
lobular carcinoma
,
invasive hydatidiform mole
,
pancreatic ductal carcinoma
,
ductal carcinoma
,
myoepithelioma
,
radiotherapy
,
adenosquamous carcinoma
,
breast neoplasms
,
recurrence
,
biliary tract neoplasms
,
uterine cervical neoplasms
,
urinary bladder neoplasms
,
neoadjuvant therapy
Benzimidazole
prostatic neoplasms
Aglatimagene besadenovec
prostatic neoplasms
Alisertib
recurrence
,
colorectal neoplasms
,
mucinous adenocarcinoma
,
colonic neoplasms
,
rectal neoplasms
,
cystadenocarcinoma
,
head and neck neoplasms
,
gastrointestinal neoplasms
,
digestive system neoplasms
,
urogenital neoplasms
,
central nervous system neoplasms
,
melanoma
,
thoracic neoplasms
,
hematologic neoplasms
,
multiple myeloma
,
b-cell chronic lymphocytic leukemia
,
large-cell lymphoma anaplastic
,
immunoblastic lymphadenopathy
,
enteropathy-associated t-cell lymphoma
,
female genital neoplasms
,
lip neoplasms
,
male genital neoplasms
,
papilloma
,
brain neoplasms
,
glioblastoma
,
glioma
,
gliosarcoma
,
ependymoma
,
astrocytoma
,
oligodendroglioma
,
neoplasms
,
lymphoma
,
large b-cell lymphoma diffuse
,
follicular lymphoma
,
burkitt lymphoma
,
breast neoplasms
,
mantle-cell lymphoma
,
adenocarcinoma
,
lung neoplasms
,
b-cell lymphoma
,
ovarian neoplasms
,
small cell lung carcinoma
,
prostatic neoplasms
,
non-small-cell lung carcinoma
,
b-cell lymphoma marginal zone
,
waldenstrom macroglobulinemia
,
leukemia
,
t-cell lymphoma
,
teratoma
,
rhabdoid tumor
,
phenylketonurias
,
fallopian tube neoplasms
,
ovarian epithelial carcinoma
,
peritoneal neoplasms
,
malignant mesothelioma
,
mesothelioma
,
squamous cell carcinoma of head and neck
,
carcinoma
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
myeloid leukemia
,
preleukemia
,
syndrome
,
non-hodgkin lymphoma
,
t-cell lymphoma cutaneous
,
t-cell lymphoma peripheral
,
primary myelofibrosis
,
megakaryoblastic leukemia acute
Edrecolomab
hypertension
,
hiv infections
,
hiv
,
acquired immunodeficiency syndrome
,
immunologic deficiency syndromes
,
neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
transitional cell carcinoma
,
breast neoplasms
,
renal cell carcinoma
,
urologic neoplasms
,
carcinoma
,
stomach neoplasms
,
head and neck neoplasms
,
squamous cell carcinoma of head and neck
,
melanoma
,
squamous cell carcinoma
,
mouth neoplasms
,
oropharyngeal neoplasms
,
squamous cell neoplasms
,
neoplasms by histologic type
,
neoplasms by site
,
glandular and epithelial neoplasms
,
hypopharyngeal neoplasms
,
hepatitis c
,
chronic hepatitis c
,
hepatitis
,
hepatitis a
,
malignant mesothelioma
,
mesothelioma
,
lymphoma
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
pancreatic ductal carcinoma
,
biliary tract neoplasms
,
invasive hydatidiform mole
,
ovarian neoplasms
Lornoxicam
leukemia
,
myelodysplastic syndromes
,
hematologic neoplasms
,
graft vs host disease
,
preleukemia
,
syndrome
Aspartame
medical sociology
,
infections
,
renal insufficiency
,
venous thrombosis
,
salivary gland neoplasms
,
breast neoplasms
,
neoplasms
,
colorectal neoplasms
,
non-small-cell lung carcinoma
,
thyroid neoplasms
,
sarcoma
,
melanoma
,
biliary tract neoplasms
,
obstructive sleep apnea
,
sleep apnea syndromes
,
apnea
,
chronic renal insufficiency
,
kidney diseases
,
x-linked bulbo-spinal atrophy
,
heart failure
,
thromboembolism
,
non-hodgkin lymphoma
,
human experimentation
,
venous thromboembolism
,
lymphoma
,
contraception
,
pulmonary hypertension
,
pulmonary arterial hypertension
,
stroke
,
respiratory insufficiency
,
communicable diseases
,
rheumatic diseases
,
prostatic neoplasms
,
castration-resistant prostatic neoplasms
,
macular edema
,
retinal vein occlusion
,
wounds and injuries
,
wound healing
,
postmenopause
,
endometriosis
,
chronic pain
,
interstitial cystitis
,
pelvic pain
,
syndrome
Bevifimod
sarcoma
,
hiv infections
,
kaposi sarcoma
Doxecitine
b-cell lymphoma
,
glioma
,
liver neoplasms
,
unknown primary neoplasms
,
nasopharyngeal neoplasms
,
esophageal neoplasms
,
biliary tract neoplasms
,
uterine cervical neoplasms
,
hepatocellular carcinoma
,
brain stem neoplasms
,
brain neoplasms
,
hodgkin disease
,
aids-related lymphoma
,
extranodal nk-t-cell lymphoma
,
recurrence
,
clear cell adenocarcinoma
,
invasive hydatidiform mole
,
bile duct neoplasms
,
gallbladder neoplasms
,
erythema multiforme
,
hiv infections
,
stomach neoplasms
,
acquired immunodeficiency syndrome
,
aids-related complex
,
neoplasms
,
neoplasm metastasis
,
adenocarcinoma
,
lymphoma
,
transitional cell carcinoma
,
large b-cell lymphoma diffuse
,
urologic neoplasms
,
urinary bladder neoplasms
,
head and neck neoplasms
,
ovarian neoplasms
,
non-hodgkin lymphoma
,
triple negative breast neoplasms
,
chronic hepatitis
,
carcinoma
,
lung neoplasms
,
neoplasms by site
,
ductal carcinoma breast
,
respiratory tract diseases
,
germ cell and embryonal neoplasms
,
small cell lung carcinoma
,
lung diseases
,
respiratory tract neoplasms
,
bronchogenic carcinoma
,
thoracic neoplasms
,
bronchial diseases
,
neoplasms by histologic type
,
nerve tissue neoplasms
,
kidney diseases
,
aids-associated nephropathy
,
ovarian epithelial carcinoma
,
lobular carcinoma
,
skin diseases
,
breast diseases
,
breast neoplasms
,
colorectal neoplasms
,
non-small-cell lung carcinoma
,
pancreatic neoplasms
,
rectal neoplasms
,
colonic neoplasms
,
hepatitis b
,
chronic hepatitis b
,
hepatitis
,
hepatitis a
Nepidermin
colorectal neoplasms
,
adenocarcinoma
,
rectal neoplasms
,
squamous cell carcinoma of head and neck
,
chronic obstructive pulmonary disease
,
meningioma
,
multiple myeloma
,
gliosarcoma
,
nasopharyngeal carcinoma
,
nasopharyngeal neoplasms
,
glioma
,
central nervous system neoplasms
,
nervous system neoplasms
,
breast neoplasms
,
macular edema
,
non-small-cell lung carcinoma
,
leukemia
,
vision disorders
,
bcr-abl positive chronic myelogenous leukemia
,
neoplasm metastasis
,
melanoma
,
arthritis
,
neoplasms
,
myeloid leukemia
,
spondylarthritis
,
spondylitis
,
edema
,
carcinoma
,
psoriatic arthritis
,
ankylosing spondylitis
,
retinal vein occlusion
,
lung neoplasms
,
chronic urticaria
,
low vision
,
cystic fibrosis
,
syndrome
,
choroidal neovascularization
,
osteitis deformans
,
renal cell carcinoma
,
philadelphia chromosome
,
ovarian neoplasms
,
pituitary acth hypersecretion
,
fibrosis
,
heartburn
,
myelodysplastic syndromes
,
preleukemia
,
thrombocytopenia
,
diabetic retinopathy
,
retinal neovascularization
,
macular degeneration
,
sarcoma
,
hematologic diseases
,
sickle cell anemia
,
sickle cell trait
,
vaso-occlusive crises
,
fever
,
hyperthermia
,
skin neoplasms
,
stomatitis
,
neuroendocrine tumors
,
lymphoma
,
glioblastoma
,
gastrointestinal stromal tumors
,
triple negative breast neoplasms
,
myeloid leukemia acute
,
acth-secreting pituitary adenoma
,
uveitis
,
pseudomonas aeruginosa
,
b-cell chronic lymphocytic leukemia
,
lymphoid leukemia
,
respiratory aspiration
,
prostatic neoplasms
,
myelomonocytic leukemia chronic
,
myelomonocytic leukemia juvenile
,
wet macular degeneration
,
pathologic neovascularization
,
adenocarcinoma of lung
,
brain neoplasms
,
iron overload
,
hepatocellular carcinoma
,
stomach neoplasms
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
carcinoid tumor
,
malignant carcinoid syndrome
,
serotonin syndrome
,
astrocytoma
,
hypercholesterolemia
,
hyperlipoproteinemia type ii
,
homozygous familial hypercholesterolemia
,
urticaria
,
lupus nephritis
,
nephritis
,
axial spondyloarthritis
,
endometrioid carcinoma
,
fallopian tube neoplasms
,
peritoneal neoplasms
,
allergic rhinitis seasonal
,
graft vs host disease
,
primary myelofibrosis
,
myositis
,
inclusion body myositis
,
juvenile arthritis
,
hereditary autoinflammatory diseases
,
amyloidosis
,
familial mediterranean fever
,
diabetes mellitus
,
rheumatoid arthritis
,
hereditary sensory and autonomic neuropathies
,
psoriasis
,
hyperlipoproteinemia type i
,
hyperpituitarism
,
degenerative myopia
,
asthma
,
non-hodgkin lymphoma
,
acromegaly
,
pulmonary infarction
,
hodgkin disease
,
behcet syndrome
,
osteoporosis
,
postmenopause
,
disease
,
giant cell arteritis
,
vasculitis
,
thyroid neoplasms
,
food hypersensitivity
,
peanut hypersensitivity
,
polymyalgia rheumatica
,
male breast neoplasms
,
recurrence
,
follicular lymphoma
,
polycythemia vera
,
polycythemia
,
mucositis
,
myeloid leukemia chronic-phase
,
proteinuria
,
iga glomerulonephritis
,
heart failure
,
left ventricular hypertrophy
,
pathologic dilatation
,
hypertension
,
essential hypertension
,
systolic murmurs
Polyglycolic acid
iron-deficiency anemia
,
iron deficiencies
Globulin, immune
healthy volunteers/patients
,
myeloid leukemia acute
,
myeloid leukemia
,
myelodysplastic syndromes
,
myeloproliferative disorders
,
primary myelofibrosis
,
macular degeneration
,
ulcer
,
plasmacytoma
,
preleukemia
,
soft tissue neoplasms
,
hepatitis b
,
chronic hepatitis b
,
hepatitis
,
herpesviridae infections
,
hepatitis a
,
infections
,
plasmablastic lymphoma
,
large-cell lymphoma immunoblastic
,
ichthyosis
,
renal cell carcinoma
,
urologic neoplasms
,
kidney neoplasms
,
neoplasm metastasis
,
essential thrombocythemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
bcr-abl positive chronic myelogenous leukemia
,
hodgkin disease
,
aplastic anemia
,
neoplasms
,
prostatic neoplasms
,
non-small-cell lung carcinoma
,
hematologic neoplasms
,
syndrome
,
hidradenitis suppurativa
,
smoldering multiple myeloma
,
immunoglobulin light-chain amyloidosis
,
renal insufficiency
,
atopic dermatitis
,
eczema
,
dermatitis
,
adenocarcinoma
,
hidradenitis
,
paraproteinemias
,
monoclonal gammopathy of undetermined significance
,
inflammation
,
virus diseases
,
amyloidosis
,
hiv infections
,
castration-resistant prostatic neoplasms
,
carcinoma
,
ovarian neoplasms
,
fallopian tube neoplasms
,
peritoneal neoplasms
,
adenocarcinoma of lung
,
biliary liver cirrhosis
,
peripheral arterial disease
,
castleman disease
,
alzheimer disease
,
dementia
,
cognitive dysfunction
,
acne vulgaris
,
type 2 diabetes mellitus
,
diabetes mellitus
,
lung neoplasms
,
hematologic diseases
,
bone marrow diseases
,
poems syndrome
,
cytokine release syndrome
,
small cell carcinoma
,
small cell lung carcinoma
,
neuroendocrine carcinoma
,
glioblastoma
,
glioma
,
gliosarcoma
,
astrocytoma
,
diffuse intrinsic pontine glioma
,
optic nerve glioma
,
brain stem neoplasms
,
hiv
,
acquired immunodeficiency syndrome
,
sexually transmitted diseases
,
retroviridae infections
,
immunologic deficiency syndromes
,
viral sexually transmitted diseases
,
pancreatic neoplasms
,
triple negative breast neoplasms
,
sickle cell anemia
,
residual neoplasm
,
plasma cell neoplasms
,
rheumatoid arthritis
,
non-hodgkin lymphoma
,
b-cell lymphoma
,
recurrence
,
b-cell chronic lymphocytic leukemia
,
large b-cell lymphoma diffuse
,
leukemia
,
juvenile arthritis
,
systemic lupus erythematosus
,
mantle-cell lymphoma
,
colorectal neoplasms
,
follicular lymphoma
,
axial spondyloarthritis
,
colitis
,
lymphoid leukemia
,
waldenstrom macroglobulinemia
,
b-cell lymphoma marginal zone
,
skin diseases
,
prolymphocytic leukemia t-cell
,
neonatal alloimmune thrombocytopenia
,
pouchitis
,
multiple myeloma
,
psoriasis
,
crohn disease
,
lymphoma
,
psoriatic arthritis
,
ulcerative colitis
,
arthritis
,
ankylosing spondylitis
,
inflammatory bowel diseases
,
spondylarthropathies
,
spondylarthritis
,
spondylitis
,
cardiovascular diseases
,
chronic kidney failure
,
pure red-cell aplasia
,
anemia
,
kidney diseases
,
hepatitis c
,
congenital abnormalities
,
autoimmune diseases
,
pregnancy
,
lymphoproliferative disorders
Digitalis
neoplasms
Hyoscyamine
breast neoplasms
,
adenocarcinoma
Anthracycline
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
1
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