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Company ReportsPuma Biotechnology

Puma Biotechnology(PBYI)

Puma Biotechnology is a publicly traded biopharmaceutical company (NASDAQ: PBYI) headquartered in Los Angeles, CA.

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Marketed Drugs

Clinical Trials

Financial

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Nerlynx	Neratinib	2017-07-17	2025-2031	Breast neoplasms

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

hematologic neoplasms

,

myeloproliferative disorders

,

non-hodgkin lymphoma

,

primary myelofibrosis

,

multiple myeloma

,

precursor cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

bcr-abl positive chronic myelogenous leukemia

,

myelomonocytic leukemia chronic

,

,

hodgkin disease

,

leukemia myeloid chronic atypical bcr-abl negative

,

myelodysplastic-myeloproliferative diseases

,

myeloid leukemia chronic-phase

,

myeloid leukemia accelerated phase

,

,

,

,

,

,

hepatic insufficiency

,

gastrointestinal neoplasms

,

esophageal squamous cell carcinoma

,

,

neoplasm metastasis

,

triple negative breast neoplasms

,

brain neoplasms

,

stomach neoplasms

,

pancreatic neoplasms

,

non-small-cell lung carcinoma

,

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

,

colorectal neoplasms

,

,

ovarian neoplasms

,

inflammatory breast neoplasms

,

neurofibromatosis 2

,

acoustic neuroma

,

,

,

hemangiosarcoma

,

pathologic complete response

,

hereditary sensory and autonomic neuropathies

,

colonic neoplasms

,

disease progression

,

,

,

,

central nervous system neoplasms

,

,

endometrial neoplasms

,

fallopian tube neoplasms

,

lobular carcinoma

,

invasive hydatidiform mole

,

,

pancreatic ductal carcinoma

,

,

,

adenosquamous carcinoma

,

breast neoplasms

,

,

biliary tract neoplasms

,

uterine cervical neoplasms

,

urinary bladder neoplasms

,

neoadjuvant therapy

Aglatimagene besadenovec

,

,

triple negative breast neoplasms

,

,

pharmacokinetics

,

healthy volunteers/patients

,

pharmacological phenomena

,

breast neoplasms

,

,

,

ovarian neoplasms

,

pancreatic neoplasms

,

non-small-cell lung carcinoma

,

colorectal neoplasms

,

uterine cervical neoplasms

,

endometrial neoplasms

,

stomach neoplasms

,

urinary bladder neoplasms

,

small cell lung carcinoma

,

biliary tract neoplasms

,

,

,

hereditary sensory and autonomic neuropathies

,

hereditary breast and ovarian cancer syndrome

,

,

fallopian tube neoplasms

,

,

head and neck neoplasms

,

dna repair-deficiency disorders

,

,

x-linked bulbo-spinal atrophy

,

neoplasm metastasis

,

,

,

prostatic neoplasms

,

castration-resistant prostatic neoplasms

,

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

small cell lung carcinoma

,

breast neoplasms

,

,

myeloid leukemia acute

,

deficiency diseases

,

paraproteinemias

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

breast neoplasms

,

immune system diseases

,

hematologic neoplasms

,

type 2 diabetes mellitus

,

,

metabolic diseases

,

,

glycogen storage disease

,

,

immunoglobulin g4-related disease

,

,

myeloid leukemia

,

,

falciparum malaria

,

,

,

,

,

polycystic kidney diseases

,

autosomal dominant polycystic kidney

,

,

,

renal insufficiency

,

hematologic diseases

,

blood protein disorders

,

neoplasms by histologic type

,

prostatic neoplasms

,

circulating neoplastic cells

,

x-linked bulbo-spinal atrophy

,

heart transplantation

,

non-small-cell lung carcinoma

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

esophageal neoplasms

,

,

neoplasm metastasis

,

aplastic anemia

,

multiple myeloma

,

hypercholesterolemia

,

meningococcal infections

,

plasma cell neoplasms

,

hemolytic anemia autoimmune

,

,

meningococcal meningitis

,

stomach neoplasms

,

,

kidney diseases

,

gaucher disease

,

,

chronic renal insufficiency

,

hyperphosphatemia

,

multiple sclerosis

,

,

homozygous familial hypercholesterolemia

,

hyperlipoproteinemia type ii

,

,

,

healthy volunteers/patients

,

,

glycogen storage disease type ii

,

atopic dermatitis

,

diabetes mellitus

,

insulin resistance

,

,

glycogen storage disease type iii

,

,

non-hodgkin lymphoma

,

,

postmenopausal osteoporosis

,

,

lymphoproliferative disorders

complex regional pain syndromes

,

,

,

,

,

,

stress urinary incontinence

,

,

prostatic hyperplasia

,

choroidal neovascularization

,

,

diabetes mellitus

,

magnetic resonance imaging

,

,

,

hypertrophic cicatrix

,

,

major depressive disorder

,

carpal tunnel syndrome

,

premature ejaculation

,

,

rectal neoplasms

,

low anterior resection syndrome

,

,

penile induration

,

thoracic outlet syndrome

,

postherpetic neuralgia

,

motor neuron disease

,

thyroid diseases

,

,

ovarian neoplasms

,

stomach neoplasms

,

head and neck neoplasms

,

esophageal neoplasms

,

,

urinary bladder neoplasms

,

small cell lung carcinoma

,

endophthalmitis

,

lacrimal apparatus diseases

,

,

radiation injuries

,

uveal neoplasms

,

,

pancreatic neoplasms

,

macular degeneration

,

,

breast neoplasms

,

myofascial pain syndromes

,

neurogenic urinary bladder

,

,

,

,

,

non-small-cell lung carcinoma

,

dystonic disorders

,

temporomandibular joint disorders

,

,

,

somatoform disorders

,

systemic scleroderma

,

raynaud disease

,

diffuse scleroderma

,

urinary bladder diseases

,

multiple sclerosis

,

,

postoperative pain

,

breast diseases

,

hereditary breast and ovarian cancer syndrome

,

,

,

,

patellofemoral pain syndrome

,

allergic conjunctivitis

,

,

muscle spasticity

,

overactive urinary bladder

,

urinary incontinence

,

migraine disorders

,

,

,

,

healthy volunteers/patients

,

,

,

dry eye syndromes

,

,

prostatic neoplasms

,

diabetic retinopathy

,

parkinson disease

,

,

,

,

,

chronic kidney failure

,

renal insufficiency

,

iron-deficiency anemia

,

iron deficiencies

,

,

interstitial cystitis

,

graves ophthalmopathy

,

,

,

spinal cord injuries

,

developmental disabilities

,

,

,

left ventricular hypertrophy

,

,

sjogren's syndrome

,

retinal vein occlusion

,

herpes labialis

,

traumatic brain injuries

,

,

,

,

keratoconjunctivitis sicca

,

,

,

muscle strength

,

clostridium botulinum type a

colorectal neoplasms

,

,

rectal neoplasms

,

squamous cell carcinoma of head and neck

,

chronic obstructive pulmonary disease

,

urinary bladder neoplasms

,

,

multiple myeloma

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

,

non-small-cell lung carcinoma

,

vision disorders

,

bcr-abl positive chronic myelogenous leukemia

,

,

,

neoplasm metastasis

,

,

,

myeloid leukemia

,

spondylarthritis

,

,

,

,

psoriatic arthritis

,

ankylosing spondylitis

,

retinal vein occlusion

,

chronic urticaria

,

,

,

cystic fibrosis

,

choroidal neovascularization

,

osteitis deformans

,

renal cell carcinoma

,

philadelphia chromosome

,

ovarian neoplasms

,

pituitary acth hypersecretion

,

,

,

myelodysplastic syndromes

,

thrombocytopenia

,

,

diabetic retinopathy

,

retinal neovascularization

,

macular degeneration

,

,

hematologic diseases

,

sickle cell anemia

,

sickle cell trait

,

vaso-occlusive crises

,

,

,

,

,

neuroendocrine tumors

,

,

,

gastrointestinal stromal tumors

,

triple negative breast neoplasms

,

myeloid leukemia acute

,

acth-secreting pituitary adenoma

,

,

pseudomonas aeruginosa

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

respiratory aspiration

,

prostatic neoplasms

,

iga glomerulonephritis

,

myelomonocytic leukemia chronic

,

,

wet macular degeneration

,

pathologic neovascularization

,

adenocarcinoma of lung

,

brain neoplasms

,

,

hepatocellular carcinoma

,

stomach neoplasms

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

carcinoid tumor

,

malignant carcinoid syndrome

,

serotonin syndrome

,

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

homozygous familial hypercholesterolemia

,

non-radiographic axial spondyloarthritis

,

,

lupus nephritis

,

,

axial spondyloarthritis

,

endometrioid carcinoma

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

allergic rhinitis seasonal

,

graft vs host disease

,

primary myelofibrosis

,

,

inclusion body myositis

,

juvenile arthritis

,

hereditary autoinflammatory diseases

,

,

familial mediterranean fever

,

diabetes mellitus

,

rheumatoid arthritis

,

hereditary sensory and autonomic neuropathies

,

,

hyperlipoproteinemia type i

,

hyperpituitarism

,

degenerative myopia

,

,

non-hodgkin lymphoma

,

,

pulmonary infarction

,

hodgkin disease

,

behcet syndrome

,

,

,

,

giant cell arteritis

,

,

pancreatic ductal carcinoma

,

thyroid neoplasms

,

food hypersensitivity

,

peanut hypersensitivity

,

polymyalgia rheumatica

,

male breast neoplasms

,

,

follicular lymphoma

,

polycythemia vera

,

,

,

myeloid leukemia chronic-phase

,

,

chronic renal insufficiency

,

kidney diseases

,

glomerulonephritis

,

urologic diseases

,

sjogren's syndrome

,

autoimmune diseases

,

,

breast neoplasms

,

,

left ventricular hypertrophy

,

pathologic dilatation

,

,

essential hypertension

,

systolic murmurs

,

disease progression

Globulin, immune

healthy volunteers/patients

,

myeloid leukemia acute

,

myelodysplastic syndromes

,

macular degeneration

,

,

,

monoclonal gammopathy of undetermined significance

,

myeloid leukemia

,

,

soft tissue neoplasms

,

,

chronic hepatitis b

,

,

,

herpesviridae infections

,

,

myeloproliferative disorders

,

,

plasmablastic lymphoma

,

,

renal cell carcinoma

,

urologic neoplasms

,

kidney neoplasms

,

neoplasm metastasis

,

primary myelofibrosis

,

precursor cell lymphoblastic leukemia-lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

hodgkin disease

,

aplastic anemia

,

gastrointestinal neoplasms

,

,

prostatic neoplasms

,

non-small-cell lung carcinoma

,

hematologic neoplasms

,

immunoglobulin light-chain amyloidosis

,

,

hidradenitis suppurativa

,

smoldering multiple myeloma

,

renal insufficiency

,

atopic dermatitis

,

,

,

,

,

paraproteinemias

,

,

,

castration-resistant prostatic neoplasms

,

cytokine release syndrome

,

,

ovarian neoplasms

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

adenocarcinoma of lung

,

biliary liver cirrhosis

,

peripheral arterial disease

,

castleman disease

,

alzheimer disease

,

,

cognitive dysfunction

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

hematologic diseases

,

bone marrow diseases

,

,

small cell carcinoma

,

small cell lung carcinoma

,

neuroendocrine carcinoma

,

,

,

,

,

diffuse intrinsic pontine glioma

,

optic nerve glioma

,

brain stem neoplasms

,

,

acquired immunodeficiency syndrome

,

retroviridae infections

,

viral sexually transmitted diseases

,

pancreatic neoplasms

,

triple negative breast neoplasms

,

sickle cell anemia

,

residual neoplasm

,

plasma cell neoplasms

,

rheumatoid arthritis

,

non-hodgkin lymphoma

,

,

b-cell chronic lymphocytic leukemia

,

b-cell lymphoma

,

large b-cell lymphoma diffuse

,

juvenile arthritis

,

,

colorectal neoplasms

,

systemic lupus erythematosus

,

follicular lymphoma

,

mantle-cell lymphoma

,

axial spondyloarthritis

,

,

lymphoid leukemia

,

waldenstrom macroglobulinemia

,

b-cell lymphoma marginal zone

,

,

prolymphocytic leukemia t-cell

,

neonatal alloimmune thrombocytopenia

,

,

multiple myeloma

,

,

,

,

psoriatic arthritis

,

ulcerative colitis

,

,

ankylosing spondylitis

,

inflammatory bowel diseases

,

spondylarthropathies

,

spondylarthritis

,

,

cardiovascular diseases

,

chronic kidney failure

,

pure red-cell aplasia

,

,

kidney diseases

,

,

congenital abnormalities

,

autoimmune diseases

,

,

lymphoproliferative disorders

atrial fibrillation

,

cardiac arrhythmias

breast neoplasms

,

neoplasm metastasis

,

,

,

,

hemangiosarcoma

,

synovial sarcoma

,

rhabdomyosarcoma

,

neurofibrosarcoma

,

malignant fibrous histiocytoma

,

nerve sheath neoplasms

,

myelodysplastic syndromes

,

lymphoid leukemia

,

myeloid leukemia

,

thrombocytopenia

,

,

mantle-cell lymphoma

,

bcr-abl positive chronic myelogenous leukemia

,

,

male breast neoplasms

,

breast neoplasms

,

myeloid leukemia acute

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

congenital abnormalities

,

brain neoplasms

,

lobular carcinoma

,

ductal carcinoma breast

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

myelomonocytic leukemia acute

,

basophilic leukemia acute

,

erythroblastic leukemia acute

,

eosinophilic leukemia acute

,

multiple myeloma

,

,

ovarian neoplasms

,

fallopian tube neoplasms

,

peritoneal neoplasms

,

,

follicular lymphoma

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